Historically, sacred cities have been instrumental in constructing and perpetuating spiritual and cultural identities. Vrindavan is a city of profound religious significance in the Braj region of northern India. The city has undergone a remarkable evolution, originating as a dense forest renowned for its sacred Tulasi (holy basil) groves, offering an immersive landscape-based spiritual experience in the ancient past. It gradually developed into an organic settlement dominated by temple-centric spatial organisation. However, recent decades have witnessed Vrindavan’s transformation into a rapidly expanding urban centre, driven by the pressures of burgeoning tourism and the pervasive influence of globalisation. This shift has led to profound changes in the city’s spatial and social fabric, with the commercialisation of religious spaces and the decline of communal areas such as ghats, chowks (main streets, a plaza), and kunj galis (Alameda), resulting in the erosion of architectural heritage and spiritual identity of Vrindavan. This chapter integrates spatial analysis with ethnographic insights to document the multifaceted impacts of Vrindavan’s transformation into a religious tourism hub. Concerning the emerging urban religious landscapes in South Asia, the study proposes a ‘sacred sustainability’ framework—a holistic urban development model that seeks to balance modernisation with preserving Vrindavan’s cultural and sacred heritage.