This chapter provides complex insights on how urban water governance challenges influence the water–health nexus because of the political instrumentalization of potable water. Concurrently, post-1980, the urban water infrastructural systems have increasingly depreciated, thereby leading to potable water challenges. In retrospect, this study highlights the water–health nexus because Zimbabwe has a history of frequent, severe cholera outbreaks that have resulted in at least 5000 deaths per outbreak on average; most people who died fell into the category of people living in poverty. The cholera pandemic is a stark illustration of the unique problems underpinning urban water service delivery, which fosters a favorable setting for a wide range of waterborne challenges. Furthermore, due to Zimbabwe’s hyperinflationary economy, which obstructs low-income households from accessing alternative sources of potable water, people living in poverty are more prone to suffering from a wide range of water-related health diseases. As a result, the numerous health implications caused by fissures and cracks in the urban water governance structures must not be overlooked. The study also argues on how these health inferences extend beyond the generic waterborne diseases and reflect on how urban water challenges have created emotional and psychological stress, particularly for females who bear the household burden of ensuring the accessibility of potable water. In essence, the study makes the case that a complex range of factors, including groundwater contamination, infrastructural challenges, politicization of water bodies, and patterns of global climate change, are also unquestionably to blame for the urban water services sector’s inability to deliver potable water efficiently and effectively. Thus, as the chapter’s conclusion underscores, water is an essential element of sustainable development and ensuring human health and well-being. In conclusion, this study illuminates the pervasive influence of political interests on urban water governance in Zimbabwe and its detrimental consequences for public health and sustainable development.