This work presents a system for mass parallel automatic synthesis of oligonucleotides utilizing inkjet printing technology. The system is designed for high-throughput synthesis, featuring a microcontroller-based control architecture that precisely manages reagent delivery and synthesis operations. Key functionalities include the automation of oligonucleotide sequence assignment and the execution of synthesis steps such as detritylation, washing, and oxidation. The system’s design ensures high-density synthesis on porous substrates, optimizing reagent application to prevent lateral spreading and achieve accurate synthesis. This approach aims to enhance the efficiency and scalability of oligonucleotide synthesis, providing a robust platform for applications in fields such as next-generation sequencing.