In Mexico, the problem of contaminated soils has become increasingly important due to its impact on human health, ecosystems, and urban development. Historically, soil contamination began to intensify with the rise of industrialization in the mid-twentieth century, especially in urban and industrial areas such as the Valley of Mexico, Monterrey, and Guadalajara. Activities such as mining, the chemical industry, improper management of hazardous waste, and accidental hydrocarbon spills have been the main sources of contamination. For decades, the lack of environmental regulation allowed the uncontrolled disposal of waste and the use of highly polluting industrial practices. It was not until the enactment of environmental laws, such as the General Law on Ecological Balance and Environmental Protection (LGEEPA; for its acronym in Spanish) in 1988 and the creation of the Federal Attorney for Environmental Protection (PROFEPA; for its acronym in Spanish), that criteria and mechanisms for control and remediation began to be established. Currently, the Ministry of Environment and Natural Resources (SEMARNAT; for its acronym in Spanish) maintains an inventory of contaminated sites, primarily with heavy metals, solvents, and industrial waste. However, this record is limited and does not reflect the total number of affected sites. More than 4000 sites have been identified, but many more remain unevaluated and unremediated, in part due to technical, legal, and budgetary constraints. Managing contaminated soils in Mexico remains a challenge. Legislation must be strengthened, funding mechanisms expanded, and research and citizen participation encouraged to advance effective remediation and prevent future harms.