Since 2000, the Database of Individual Patients’ Experience of Illness (DIPEx) International project has been a benchmark for reporting patients’ illness experiences through rigorous qualitative research. This process ensures the reliability of the information presented in DIPEx’s online resources, accessed more than four million times yearly. The DIPEx project’s international collaboration fosters a global network that considers cultural and social nuances in health. There are 14 participating countries, including Brazil, since 2019 (The only member of the Global South). DIPEx members are from various health sciences disciplines, such as sociology, psychology, anthropology, medicine, and nursing. Dipex Brazil originated at UFRJ and expanded as a collaborative consortium with other Brazilian public universities (UERJ, USP, UNESP, UFBA, and UNB). The researchers were trained in the DIPEx method, a rigorous and comprehensive qualitative research approach developed at the Department of Primary Care and Health Sciences of the University of Oxford. This method, which involves in-depth interviews and thematic analysis, underscores the project's commitment to high-quality research. The DIPEx Brazil project has produced two modules on leprosy: 1. The experience of leprosy patients. 2. The experience of their healthcare team, and two modules on COVID-19: 1. The experiences of patients with severe COVID-19 in intensive care units. 2. The experiences of primary care professionals who worked at the front line during the pandemic. As an innovative and inclusive platform for health communication, DIPEx Brazil is designed to benefit patients, students, and professionals. Despite the challenge of doing impactful research in Latin America, our project has been consistently gaining strength.