Antibiotics that inhibit protein synthesis are discussed. Background biochemistry information on translation is provided. Antibiotics presented include puromycin, aminoglycosides, tetracyclines, chloramphenicol, macrolides, lincosamides, streptogramins oxazolidinones, pleuromutilins, mupirocins, and peptide deformylase inhibitors. Mechanisms of action of the antibiotics and resistance development against them are discussed.

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Antibiotics That Inhibit Protein Synthesis

  • Mrinal K. Bhattacharjee

摘要

Antibiotics that inhibit protein synthesis are discussed. Background biochemistry information on translation is provided. Antibiotics presented include puromycin, aminoglycosides, tetracyclines, chloramphenicol, macrolides, lincosamides, streptogramins oxazolidinones, pleuromutilins, mupirocins, and peptide deformylase inhibitors. Mechanisms of action of the antibiotics and resistance development against them are discussed.