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The loss of absorptive surface and the accelerated transit time are the main factors that determine the severity of the intestinal failure in short bowel syndrome patients. The length of the resection, the anatomical part of the remaining intestine with the consequent loss of site-specific transport processes and of site-specific gastrointestinal hormones producing cells, are associated with a large spectrum of nutritional deficiencies. A concise review of the pathophysiology of SBS is provided.

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Pathophysiology and Anatomical Considerations in Short Bowel Syndrome

  • 章节

  • 发表日期：

    2025年

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  • Cristian Gheorghe,
  • Roxana Vadan

摘要

The loss of absorptive surface and the accelerated transit time are the main factors that determine the severity of the intestinal failure in short bowel syndrome patients. The length of the resection, the anatomical part of the remaining intestine with the consequent loss of site-specific transport processes and of site-specific gastrointestinal hormones producing cells, are associated with a large spectrum of nutritional deficiencies. A concise review of the pathophysiology of SBS is provided.