Biopolymer-based nanoparticles show considerable promise for use in food systems since they are regarded safe, biocompatible, environmentally friendly, and adaptable carriers for encapsulating a variety of hydrophilic and hydrophobic bioactive food components. The nanoparticle of β-glucan is found to be stable even at higher temperature and pressure. The conversion of β-glucan at the nanoscale increases the bioactivity such as antitumor, immunomodulatory, applications in the field of development of medicine. Beta glucan nanoparticles are superior to other nanoparticles for encapsulation of bioactive compounds as they maintain the functionality of bioactive substances. The nano β-glucan derived from oyster mushrooms were predicted to have a high potential for application at industrial scale as an emulsifier. β-glucan nanoparticles are ideal delivery vehicles for bioactive substances because they enhance bioavailability and biological activity.