Physical strength, mobility, and lack of locomotor limitations play a crucial role in human health and social activity. Consequently, rehabilitation in orthopedics is stressed as particularly important for recovery and long-lasting life comfort. As a result, it concerns an increasing number of patients and maintaining the desired efficiency of the health system is nowadays widely considered to be moved to home care. In this paper, we study the possibility of applying inertial sensors on the body, including those built in every smartphone to supervise physical exercises driven by a simple game based on body movement. First, we built an Android-based application linking the sensor to external data collecting server. Next, we propose a server platform to integrate multiple sensor and record their signals simultaneously. The main result is the prototype environment for multipoint inertial measurement flexible to wirelessly connect phone-based or independent acceleration sensors placed in therapy-related parts of the body. The system may be developed to support a game for studying the conformance of rehabilitation protocol or to study human-tool interaction in occupational medicine or everyday living. The presented sample game was implemented and tested by 3 volunteers, but determining the effectiveness of rehabilitation requires further research with the participation of carefully selected patients.