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After more than four decades, the field of sponge biotechnology has finally overcome its most formidable obstacle: establishing a sponge cell line. Cells from the deep water marine sponge Geodia barretti divide rapidly and continuously in optimized nutrient media, clearing the path for new lines of research--whether to uncover how multicellular life evolved from unicellular organisms, study the origins of animal–microbe symbiosis, or develop production strains to industrialize new sponge-derived drugs and exploit the untapped biotechnological potential of the Porifera. Now is an exciting time in sponge biotechnology, so what’s next?

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A New Era in Sponge Cell Biotechnology

  • 章节

  • 发表日期：

    2025年

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  • Kylie Hesp,
  • Dirk E. Martens,
  • Rene H. Wijffels,
  • Shirley A. Pomponi

摘要

After more than four decades, the field of sponge biotechnology has finally overcome its most formidable obstacle: establishing a sponge cell line. Cells from the deep water marine sponge Geodia barretti divide rapidly and continuously in optimized nutrient media, clearing the path for new lines of research--whether to uncover how multicellular life evolved from unicellular organisms, study the origins of animal–microbe symbiosis, or develop production strains to industrialize new sponge-derived drugs and exploit the untapped biotechnological potential of the Porifera. Now is an exciting time in sponge biotechnology, so what’s next?