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This study aimed to compare the effectiveness between low-cost Bubble CPAP (continuous positive airway pressure) and conventional modalities of non-invasive ventilation (NIV) following elective extubation of term newborns (NBs). A retrospective study was conducted with 62 NBs who required non-invasive ventilatory support after extubation in a neonatal intensive care unit (NICU) between January 2016 and December 2022. The following data were collected: neonatal information, ventilatory parameters, duration of invasive and non-invasive ventilation, total length of hospital stay, and extubation success. Out of the 62 NBs analyzed, 26 (41.9%) used Bubble CPAP, and 36 (58.1%) used other modalities of NIV. In the Bubble CPAP group, the average duration of invasive mechanical ventilation was 4,645 min, the duration of NIV use was 2,547.5 min, and the length of stay in the NICU was 21 days. In the group that received other modalities of NIV, newborns remained on average for 8,479 min in invasive ventilation, 1,375 min in NIV, and 31 days hospitalized. The final positive end-expiratory pressure (PEEP) was significantly lower in the Bubble CPAP group (p < 0.001). It can be concluded that the use of Bubble CPAP encouraged early extubation of newborns in the studied NICU and contributed to reducing hospitalization time of term newborns.

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Comparative Analysis Between Low-Cost Bubble CPAP and Conventional Modalities of Non-Invasive Ventilation in Term Newborns

  • 会议论文

  • 发表日期：

    2025年

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  • Cristiane Coldebella,
  • Débora de Fátima Camillo Ribeiro,
  • Adriane Muller Nakato,
  • Percy Nohama

摘要

This study aimed to compare the effectiveness between low-cost Bubble CPAP (continuous positive airway pressure) and conventional modalities of non-invasive ventilation (NIV) following elective extubation of term newborns (NBs). A retrospective study was conducted with 62 NBs who required non-invasive ventilatory support after extubation in a neonatal intensive care unit (NICU) between January 2016 and December 2022. The following data were collected: neonatal information, ventilatory parameters, duration of invasive and non-invasive ventilation, total length of hospital stay, and extubation success. Out of the 62 NBs analyzed, 26 (41.9%) used Bubble CPAP, and 36 (58.1%) used other modalities of NIV. In the Bubble CPAP group, the average duration of invasive mechanical ventilation was 4,645 min, the duration of NIV use was 2,547.5 min, and the length of stay in the NICU was 21 days. In the group that received other modalities of NIV, newborns remained on average for 8,479 min in invasive ventilation, 1,375 min in NIV, and 31 days hospitalized. The final positive end-expiratory pressure (PEEP) was significantly lower in the Bubble CPAP group (p < 0.001). It can be concluded that the use of Bubble CPAP encouraged early extubation of newborns in the studied NICU and contributed to reducing hospitalization time of term newborns.