Surface treatments on biomedical implants accelerate bone formation and make surfaces more compatible. β-Titanium (β-Ti) alloys have become promising in recent years, so this study aimed to compare the influence of hydroxyapatite (HA) treatment on the physicochemical and mechanical properties of β-Ti and Ti-6Al-4V. For this, 60 discs (Ø 5 mm x 1 mm) manufactured by machining were used (n = 10) divided into: G1: Ti-6AL-4V, G2: Ti-15Mo, G3: Ti-12Mo-6Zr-2Fe, G4: Ti - 6AL-4V/HA, G5: Ti-15Mo/HA, G6: Ti-12Mo-6Zr-2Fe/HA. HA was incorporated by immersion in calcium and phosphate buffer solution. Surface roughness analyzes were carried out using confocal laser microscopy, scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS), and mechanical analyzes using microhardness and Vickers modulus of elasticity. Data distribution was verified by Shapiro-Wilk test, non-parametric analyses, Mann-Whitney U test, parametric analysis, T test and ANOVA (α = 0.05). The beginning of the deposition of HA coating was observed by SEM in the evaluated groups, confirmed by the non-detection of elements by EDS as they were below the threshold. In surface roughness analysis, notable difference was found between the machined and HA-coated groups (p < 0.05) with higher averages for the coated discs. For microhardness, the values were higher in the treated groups, but a big difference was found for G2 (p = 0.023). Regarding the modulus of elasticity, higher values were found in G1, however, without significant difference (p = 0.260). It is concluded that in all alloys evaluated, the HA coating provided an increase in surface roughness and better mechanical resistance to indentation. Furthermore, there was a change in surface morphology of the HA-coated discs with a suggestion of the beginning of deposition on the G2 and G3 discs.