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The aim of this study was to synthesize, characterize, and evaluate the antimicrobial activity of nanostructured silver vanadate decorated with silver nanoparticles (β-AgVO3) in a gel formulation against Enterococcus faecalis. β-AgVO3 was synthesized by a precipitation reaction between silver nitrate and ammonium vanadate and then characterized by transmission electron microscopy (TEM). The antimicrobial activity was analyzed using the agar diffusion test against E. faecalis. β-AgVO3 powder was obtained, which appeared macroscopically as yellowish-colored and microscopically as silver vanadate nanowires with metal spheres decorating their surface. The β-AgVO3 gel showed antimicrobial efficacy against E. faecalis, however chlorhexidine 0.12% gel was more effective. It was concluded that the synthesis of β-AgVO3 was successful and confirmed by TEM, and the gel with the nanomaterial exhibited antimicrobial activity against E. faecalis.

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Development and Antimicrobial Validation of Nanostructured Silver Vanadate Gel for Endodontic Infections

  • 会议论文

  • 发表日期：

    2025年

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  • G. L. P. Silva,
  • I. Ferreira,
  • J. M. Carvalho-Silva,
  • A. B. V. Teixeira,
  • M. A. Schiavon,
  • A. C. Reis

摘要

The aim of this study was to synthesize, characterize, and evaluate the antimicrobial activity of nanostructured silver vanadate decorated with silver nanoparticles (β-AgVO3) in a gel formulation against Enterococcus faecalis. β-AgVO3 was synthesized by a precipitation reaction between silver nitrate and ammonium vanadate and then characterized by transmission electron microscopy (TEM). The antimicrobial activity was analyzed using the agar diffusion test against E. faecalis. β-AgVO3 powder was obtained, which appeared macroscopically as yellowish-colored and microscopically as silver vanadate nanowires with metal spheres decorating their surface. The β-AgVO3 gel showed antimicrobial efficacy against E. faecalis, however chlorhexidine 0.12% gel was more effective. It was concluded that the synthesis of β-AgVO3 was successful and confirmed by TEM, and the gel with the nanomaterial exhibited antimicrobial activity against E. faecalis.