Persistent postural perceptual dizziness (abbreviated PPPD) usually occurs in the wake of some other “dizzy disease.” Most patients describe the symptom as a nonspinning disequilibrium, which fluctuates in intensity, and tends to be worse when upright, when in active or passive motion, and when exposed to complex or moving visual stimuli. Since there is not yet any confirmatory diagnostic test for PPPD, and since the symptoms can resemble those of other disorders, it is medically reasonable to undertake a screening workup (to confirm or exclude competing diagnoses). If workup reveals no more compelling diagnosis, then treatment is generally attempted with vestibular rehabilitation therapy and/or cognitive behavioral therapy. If those fail, then some practitioners advocate a trial of medications such as sertraline.