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Deficiency of vitamin B1 (thiamine) can result from malnutrition and can occur in alcoholism. Severe cases may manifest as Wernicke-Korsakoff syndrome, originally described by Karl Wernicke (1848–1905) (Wernicke K. Die akute, hämorrhagische Polioencephalitis superior [Acute hemorrhagic superior polioencephalitis]. Lehrbuch der Gehirnkrankheiten. 2. Fischer, Kassel, p 229–242, 1881; Thomson AD, Cook CC, Guerrini I, Sheedy D, Harper C, Marshall EJ. Alcohol Alcohol, 43(2):174–179, 2008) and Sergei Sergeievich Korsakoff (1853–1900) (Korsakoff SS, Vestnick Klin Psychiat Neurol, 4:1–102, 1887; Victor M, Yakovlev PI, Neurology, 5(6):394–406, 1955). Ocular motor abnormalities may be the first manifestations of vitamin B1 deficiency.

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Vitamin B1 (Thiamine) Deficiency

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  • 发表日期：

    2025年

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  • Marcello Cherchi

摘要

Deficiency of vitamin B1 (thiamine) can result from malnutrition and can occur in alcoholism. Severe cases may manifest as Wernicke-Korsakoff syndrome, originally described by Karl Wernicke (1848–1905) (Wernicke K. Die akute, hämorrhagische Polioencephalitis superior [Acute hemorrhagic superior polioencephalitis]. Lehrbuch der Gehirnkrankheiten. 2. Fischer, Kassel, p 229–242, 1881; Thomson AD, Cook CC, Guerrini I, Sheedy D, Harper C, Marshall EJ. Alcohol Alcohol, 43(2):174–179, 2008) and Sergei Sergeievich Korsakoff (1853–1900) (Korsakoff SS, Vestnick Klin Psychiat Neurol, 4:1–102, 1887; Victor M, Yakovlev PI, Neurology, 5(6):394–406, 1955). Ocular motor abnormalities may be the first manifestations of vitamin B1 deficiency.