The article considers the climatic features of air temperature in the south and south-east of the Lesser Caucasus region in 1991–2015, and the impact of regional climatic changes on the air temperature regime is predicted based on statistical indicators 2015–2021 using modern information technologies. Based on the monthly, seasonal and annual characteristics of the impact of the effects of climate change on the temperature regime, as well as long-term dynamics, the temperature fluctuations of individual areas of the region are determined. The analysis shows that the temperature in the region has risen in all months. The perennial indicator of the rise in air temperature is close to 0.8 °C. A modern temperature distribution map compiled in a geographic information system (GIS) environment shows that air temperature indicators decrease as altitude increases. The results of studying hydrometeorological conditions using modern information technologies can help identify the current state of physical and geographical conditions, reconstruct and further develop the socio-economic infrastructure.