Most people experience romantic attraction and love first during their adolescent years. While romantic relationships can be a source of health and well-being, love in adolescence is often associated with stress and depression, especially when a young person is attracted to their own gender or both genders. In this chapter, I summarize theoretical underpinnings and empirical findings around adolescent romantic experiences, and highlight gendered patterns and cross-cultural differences in love. I will demonstrate these patterns with evidence from the Health Behaviour in School-aged Children (HBSC), a World Health Organization collaborative cross-cultural study of adolescent health, conducted every four years. The HBSC international research network developed standard survey questions to measure experiences of attraction and love in 15-year-olds. These questions have been used in 13 European countries and regions in the last decade. Our working group documented cross-country differences in the prevalence of love, implying that the perception and interpretation of romantic feelings are, to some extent, influenced by cultural factors. We found health disparities across adolescents in love with opposite-, same-, and both-gender partners, or not being in love. Thus, HBSC provides epidemiological evidence for the health inequalities experienced by sexual minority (same- and both-gender attracted) youth. Sexual minority adolescents report more bullying, substance use, risky sexual behaviors, and psychosomatic symptoms than their non-minority peers. Not being in love has been protective for most health indicators. There remain, however, many unanswered questions, including the convergence of romantic attraction and other dimensions of sexual orientation.