A distinction has to be made between erotic love and love for one’s neighbor in the sense of charity. The latter in most cultures is used as a synonym for extended sympathy presupposing empathy, affection, compassion, care, reliability, and effort taking. However, the perception of a good alliance and culture by the client in psychosocial settings also complies with an ascription of competence to the professional and an early improvement of clients’ complaints. The terms “actional love and effective altruism” are outlined. Effective actional love requires basic emotional-social intelligence, knowledge about disturbances and disorders, and about intervention methods and techniques, self-care, and treatment competence including intercultural and group therapy treatment experiences. It should draw upon different value systems and concepts of meaningfulness, gender, religion, level of education, and linguistic patterns, especially in intercultural scenarios in order to promote effective charity. Furthermore, the knowledge of a critical window for success within early sessions ought to be considered. A “culture of analyzing ruptures” is suggested to deal with “difficult” patients stagnating or even failing in counseling. Recent research is confirming this stance. Case vignettes are presented to illustrate how actional love and effective charity can be realized. This chapter is an update of the article in the first edition of this handbook taking recent publications into consideration. Our view is restricted to counseling and psychotherapy as carried out by clinical psychologists, psychiatrists, counselors, and other psychosocial professionals. (Hereunder, reference is made to male, female, and diverse when using the masculine form. Likewise, the terms “psychotherapy” or “therapy” refer to all of these social professions and also include “counseling,” for in various countries there is no distinct differentiation made between the two.) A multimethod, transdiagnostic, and eclectic orientation based upon behavior therapy and psychodynamic and systemic elements is favored.