Livestock enterprises are integral to global agriculture, providing essential products and livelihoods. However, challenges such as nutritional deficiencies, rising feed costs, and environmental concerns hinder their productivity and profitability. This chapter explores practical nutritional approaches to enhance livestock production and profitability, focusing on strategies such as precision feeding, supplementation, and use of unconventional feed resources. It highlights the role of nutraceuticals, probiotics, and feed additives in improving animal health and feed efficiency. Furthermore, the economic and environmental implications of sustainable practices, including integrating crop-livestock systems, are discussed. By synthesizing evidence from recent research, this chapter offers actionable insights for farmers, policymakers, and researchers, aiming to bridge the gap between scientific knowledge and field-level application.