Objective: This study aims to evaluate medical students’ acceptance of a den-tal implant education system that integrates Mixed Reality (MR) technology with Tangible Interaction (TI). Methods: In a secure and comfortable envi-ronment, 250 medical students completed a series of dental implant tasks, including delicate tooth extraction operations and precise implant placement, using the Meta Quest 3 Head-Mounted Display (HMD) and wireless handheld controllers. Following this, participants completed a questionnaire regarding their perceptions and acceptance of the MR tangible interaction educational system. The study design is grounded in the Technology Ac-ceptance Model (TAM), incorporating tangible interaction as an additional variable to assess its role in the learning process. Results: Results indicate that 83.7% of respondents held positive attitudes towards utilizing MR tech-nology. The study hypotheses were confirmed, demonstrating that tangible interaction within mixed reality significantly enhances perceived usefulness and perceived ease of use, thereby strengthening user attitudes and ultimate usage intention. Conclusion: Mixed Reality technology effectively improves the teaching outcomes of complex skills such as dental implant surgery by providing high-quality educational resources, enhancing the realism of oper-ational practice, and increasing the precision of guidance, while overcoming the limitations of traditional physical models.