Data Conditioning to Improve Quality of Segmentation of Brain MRI Using Deep CNN Models
摘要
Accurate automatic segmentation of tumor in brain MRI scans is necessary for reproducible radiomic data extraction. Deep CNN models perform this task with reasonable accuracy. This paper proposes a new image preprocessing technique which further improves this accuracy. The pipeline consists of a Gaussian transformation of intensity (GTI) on T2-weighted images to selectively enhance the tumor bearing regions. This is coupled with an adaptive thresholding technique to localize the maximum peritumoral region. Performance was evaluated on both 2D and 3D UNet-based deep segmentation models. The Multimodal Brain Tumor Segmentation Challenge 2020 (BraTS-2020) dataset is taken for model training, validation, and testing. To assess the effectiveness of our pre-processing pipeline for both high-grade glioblastoma (HGG) and low-grade glioblastoma (LGG), BraTS 2018 and BraTS 2019 datasets have been categorized in HGG and LGG. Then, segmented results are analyzed separately for both HGG and LGG. Our segmentation results are compared with other reported models, such as 2D deep residual UNET, 3D-UNET, and nnU-Net. It is observed that the proposed data conditioning improves the performance of delineating tumors. This has been ratified by carrying out a paired t-test, a statistical significance test.