This chapter focuses on unique challenges in startup valuations in emerging markets and approaches to address them. Each emerging market has distinct characteristics compared to both other emerging markets and developed markets, including but not limited to macroeconomic factors, such as inflation and currency fluctuations, or political instability and company-specific factors caused by a startup’s unpredictable nature and their interaction with the market and third parties. Startup valuation is subjective to some extent, and there is a certain need for a reliable framework to facilitate investment decisions. The author curates 10 startup valuation methods and proposes modifications and adjustments to them, trying to combine them in a startup-specific but practical method in the context of emerging markets. Additionally, the investor perspective is highly involved in the chapter to give a solid understanding that the valuation practice is a tool to assess an investment and to build an investment decision; it is not an aim itself. And the emerging market startups can provide fruitful investment opportunities for risk-takers. The chapter also discusses important components of the valuation process such as due diligence, performance metrics, qualitative factors, portfolio strategies, exit strategies, and the regulatory scene.