What is the future university about? What has been, what is, what will be, and what should be university’s role(s) globally, and in Central Europe particularly? The chapter aims to answer these crucial questions by putting them in the context of two consecutive global crises: the first is the COVID-19 pandemic, and the second is change of the world system prompted by Russia’s full-scale invasion in Ukraine. The answers stem from the three positionalities. The first is the author’s fundamentally international education and experience; the second is the positionality of a university as a non-political institution that encounters various challenges depending on a type of political regime in which it operates. The third is positionality of Central and Eastern Europe as a crossroad of peripheries of large world empires and conflicting types of political regimes. The analysis offers a new vision of the “NEWEUropean NEWUniversity,” which may serve as a genuine regional re-developmental institution, involving education in one of global languages (English, Spanish, French, German), and in one democratically (s)elected official regional language. This conceptually new university will encompass increasing social responsibility by blending digital and outdoor learning activities, bridging primary and secondary with higher education, and scientific disciplines with vocational training.