In order to effectively combine virtual reality technology and intelligent tourism applications, a tourism platform integrating strategy formulation and virtual reality experience will be created to promote the transformation of traditional tourism to digital and personalized. In this study, semi-structured interviews were used to summarize user needs, and factor analysis was used to cluster user needs. Secondly, the AHP analytic hierarchy process was used to calculate the weights of each demand index. Finally, QFD was used to calculate the weights of characteristic indicators, 8 design functions were extracted and 4 schemes were designed, and physiological experiments and grey correlation analysis were used to determine the optimal design scheme. By integrating the theoretical models of AHP, QFD and GRA, and applying them to the design and development process of the VR application of the tourism guide, a VR application of the tourism guide was designed, which further verified the scientificity and rationality of the design process. This design process can provide reference and theoretical guidance for the design and development of the same type of VR application.