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Kidney transplantation currently stands as the best therapeutic option for end-stage renal failure in terms of quality of life and survival rate. Advances in immunosuppressive therapy and the growing immunological knowledge have paved the way towards a gradual improvement in the survival of the graft and the recipient. In spite of the increasing donations, the number of patients waiting for a transplant is also rising, mostly as a result of the growing survival on dialysis. In this chapter, the prominent features of the different types of donor are described, with a focus on deceased-donor kidney, after either brain or cardiac death, and living-donor kidney. New strategies aiming to enhance the donor pool are also tackled, e.g., the use of marginal donors with expanded criteria, new organ-reconditioning systems exploiting perfusion machines, and the circumvention of immunological barriers (AB0 incompatible transplantation and kidney paired donation programs). Management of postoperative complications and the general principles of immunosuppressive therapy are also described in detail.

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Kidney Transplant Surgery

  • 章节

  • 出版模式：

    开放获取

  • 发表日期：

    2026年

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  • Fabio Vistoli,
  • Lucia Romano,
  • Laura Lancione,
  • Antonio Giuliani,
  • Marco Clementi,
  • Elisabetta Iacobelli,
  • Martina Padula,
  • Leonardo Tersigni,
  • Franco Papola,
  • Daniela Maccarone,
  • Francesco Pisani,
  • Alessandra Panarese

摘要

Kidney transplantation currently stands as the best therapeutic option for end-stage renal failure in terms of quality of life and survival rate. Advances in immunosuppressive therapy and the growing immunological knowledge have paved the way towards a gradual improvement in the survival of the graft and the recipient. In spite of the increasing donations, the number of patients waiting for a transplant is also rising, mostly as a result of the growing survival on dialysis. In this chapter, the prominent features of the different types of donor are described, with a focus on deceased-donor kidney, after either brain or cardiac death, and living-donor kidney. New strategies aiming to enhance the donor pool are also tackled, e.g., the use of marginal donors with expanded criteria, new organ-reconditioning systems exploiting perfusion machines, and the circumvention of immunological barriers (AB0 incompatible transplantation and kidney paired donation programs). Management of postoperative complications and the general principles of immunosuppressive therapy are also described in detail.