Liquid Crystal Spatial Light Modulators (LCSLM) are devices capable of spatially and temporally modulating the amplitude and phase of incident light beams, offering versatile applications in optics. This chapter focuses on the primary applications of LCSLMs, such as beam manipulation using Computer-Generated Holography (CGH) techniques. The dynamic modulation capabilities of LCSLMs enable the implementation of CGH for wavefront sensing, which detects and measures beam aberrations. We introduce the use of LCSLMs for measuring and correcting aberrations in light beams, thereby enhancing the wavefront quality. Additionally, we present simulation and experimental results that highlight the performance of LCSLMs in these applications. Furthermore, we discuss the integration of a wavefront sensor using LCSLM, which allows for real-time measurement of wavefront aberrations.