This chapter employs close textual analysis and object-oriented ontology as its primary framework for examining the representation of ontology in the Southern Reach and Borne series. It shows how the novels challenge human superiority in science and language, offering wider implications for how we perceive the nonhuman and ourselves. By analysing the autonomous powers of the nonhuman characters and the ways in which they undermine anthropocentric assumptions in these texts, the chapter reveals how Jeff VanderMeer’s creative and experimental exploration of ontology redefines humanity’s place in the biosphere and encourages a rethinking of the human and the nonhuman that is at once humble, radical, and profoundly strange.