This paper presents an autonomous method to address challenges arising from severe lighting conditions in machine vision applications that use event cameras. To manage these conditions, the research explores the built-in potential of these cameras to adjust pixel functionality, named bias settings. As cars are driven at various times and locations, shifts in lighting conditions are unavoidable. Consequently, this paper utilizes the neuromorphic YOLO-based face tracking module of a driver monitoring system as the event-based application to study. The proposed method uses numerical metrics to continuously monitor the performance of the event-based application in real-time. When the application malfunctions, the system detects this through a drop in the metrics and automatically adjusts the event camera’s bias values. The Nelder-Mead simplex algorithm is employed to optimize this adjustment, with fine-tuning continuing until performance returns to a satisfactory level. The advantage of bias optimization lies in its ability to handle conditions such as flickering or darkness without requiring additional hardware or software. To demonstrate the capabilities of the proposed system, it was tested under conditions where detecting human faces with default bias values was impossible. These severe conditions were simulated using dim ambient light and various flickering frequencies. Following the automatic and dynamic process of bias modification, the metrics for face detection significantly improved under all conditions. Autobiasing resulted in an increase in the YOLO confidence indicators by more than 33% for object detection and 37% for face detection highlighting the effectiveness of the proposed method.