Iris Murdoch’s writings are marked by a deep engagement with the Book of Job, the earliest and perhaps most austere Judeo-Christian response to the problem of evil. Its moral lessons – that Job must abjure his self-righteousness in favour of gratitude, that the individual must endure their suffering, that there are no magical solutions to suffering – are all echoed in Murdoch’s writings. This chapter begins with a brief overview of the Book of Job and how Murdoch may have first encountered it. It then, drawing on Murdoch’s philosophical writings as well as her journals and letters, turns to her first documented engagements with the text. Arguably, the pivotal point in Murdoch’s developing interest in the Book of Job occurred in October 1964, when she was invited to contribute to a talk at Trinity College, Dublin. Thenceforth, her references to Job in her fiction increase. These fictional references subside in the 1970s in favour of a more in-depth consideration of the text in her philosophical writings, notably her 1982 Gifford Lectures. This chapter reveals that Murdoch’s dialogue with The Book of Job is diverse and wide-ranging. She not only directly mentions the text in novels like The Time of the Angels, Nuns and Soldiers and The Good Apprentice, but also, on a deeper spiritual level, is prompted by it – and by other critical engagements with it, such as those of Carol Gustav Jung – to question the sovereignty of goodness in the moral life and the ubiquity of evil and suffering.