This chapter gives an overview on the current state-of-the-art in systemic teletherapy, online systemic supervision, and online systemic training. Typologies of digitally supported mental health interventions vary, as well as terminology describing them. Due to the lack of effectiveness studies of online systemic practice, effectiveness studies of digital mental health interventions of other approaches are summarized. The digitalization of systemic therapy in the multiperson setting is the focus of the next part of the chapter. Special attention is given to the therapeutic alliance, the therapeutic process, and changes in the applied methods in systemic teletherapy. Practice recommendations and guidelines created by various professional associations follow. An overview of types and modalities of digitally supported supervision is presented, deepening the aspect of the supervisory relationship. Systematic training online is also described in its synchronous and asynchronous modalities. The chapter ends with considerations about Artificial Intelligence and psychotherapy.