This study examines the role of transportation in global supply chain management, focusing on the China Railway Express as an attractive alternative to sea, road, and air freight due to its cost and lead-time advantages. The research proposes a supply chain plan that simultaneously considers production areas and transportation routes and accounts for freight rate risk, aiming to optimize operations. The proposed model addresses uncertainties in fare structures across different routes and multiple carrier partnerships in international rail corridors. By adopting a strategic approach to route selection, businesses can balance production and transportation costs while managing market fluctuations and volatility.