Traumatic brachial plexus injuries have far-reaching psychosocial consequences, negatively impacting patients’ daily function and independence, relationships, emotional well-being, and financial security. Neuropathic pain is a complex process that accompanies traumatic brachial plexus injuries, which is strongly associated with depression and anxiety. It is important for surgeons to share clinical findings with empathy, recognizing the psychosocial impact that these long-life injuries have on each patient. Therapists play a crucial role in supporting and educating these patients throughout the continuum of care, from initial trauma through functional recovery. Therapists are well equipped to address both the physical and psychological impact of traumatic brachial plexus injuries. It is important to help patients set realistic expectations following injury and surgery to minimize disappointment while also instilling optimism.