Burke presents a detailed discussion on how behavioral research findings and best practices concerning establishing safe work environments, demonstrating positive safety leadership, and conducting effective safety training can assist in preparing employees to work safely and in safe and healthy work settings worldwide. In doing so, he emphasizes how such research findings and best practices can contribute to achieving UN 2030 sustainable development goals and targets. This discussion focuses on UN goals and targets concerning creating safe and healthy work environments for all workers, strengthening human capacity to deal with climate change and disasters, reducing traffic-related accidents and deaths, strengthening workers’ adaptive coping skills and resiliency, and strengthening the prevention of substance abuse. Importantly, he provides numerous examples of where and how interdisciplinary behavioral research insights can be applied to accelerate transformations to sustainable development by 2030 and beyond.