This chapter aims to present the bioecological theory of human development (BTHD) and its distinct contributions to a systemic understanding of human development, emphasizing its value as an analytical tool for capturing the complexity of violence against children. We begin by exploring the biography of Urie Bronfenbrenner and the personal, academic, and professional motivations that influenced his development of a widely recognized systemic theoretical model of human development. Next, we discuss how this epistemological foundation enabled a shift away from spontaneous and biologically deterministic models that sought to explain developmental processes universally, irrespective of cultural and contextual differences. Additionally, we examine different phases of Bronfenbrenner’s intellectual production, highlighting his ability to continuously refine his ideas and theoretical-methodological propositions. To familiarize readers less acquainted with his work, we outline key principles of his framework, particularly the PPCT model (person-process-context-time). Finally, we underscore the significance of his contributions for research and interventions addressing violence against children, as well as the ongoing challenges for the scientific community in advancing Bronfenbrenner’s legacy.