Applying an anti-oppressive practice (AOP) framework in community-based psychotherapy requires an assessment of the structural factors affecting a client’s presenting problems. The clinician focuses more on how oppression and power within the larger socioeconomic system of inequality alter the lives of clients. This chapter will explore how adapting an AOP framework seeks to empower marginalized clients by incorporating a resistance to oppression, along with coping strategies in a community-based mental health setting. Incorporating recent literature, this author will analyze the interconnectedness of poverty and emotional distress. Through a case exploration of a 43-year-old Latinx woman of low-socioeconomic means who suffers from bipolar disorder, this chapter will examine how power, inequality, and centuries of oppression impact marginalized individuals suffering from emotional distress. Additionally, this chapter will discuss clinical implications to assist community-based mental health clinicians in actively combating systemic oppression when providing treatment to under-resourced clients.