It is not possible to develop best practice without systematic monitoring and research. This is emphasized by the multidimensionality of dialogical practice. Psychotherapy research has provided valuable insights into the therapeutic nature of the practice. Psychiatric research, on the other hand, often emphasizes psychopathology and symptom elimination—partly because these are easier to study. However, this approach undermines the external validity of research, and treatment guidelines based on such findings frequently fail to take into account the needs of patients and their family. Studies of Open Dialogue have shown promising treatment outcomes in natural real-world settings, with results remaining at the same level for a long time. It is important to recognize that the starting point of the research, the research design, and the research methods chosen determine how its findings will be used in developing dialogical practice. Research on Open Dialogue care appears to have succeeded from the outset in creating a research model suited to care practices in real-world settings. All the studies I have conducted have examined both the patient and the clinicians at the same time. After all, mutual interaction lies at the heart of dialogic practice. Thus, a valid study cannot be conducted unless it considers all parties to the interaction.