Two areas severely affected by arsenic pollution are Bangladesh and West Bengal of India, while some studies indicated that approximately 108 countries are affected by groundwater contamination with arsenic. Bangladesh is reportedly the world’s worst arsenic disaster, with over half of its population at risk of arsenic toxicity. It is critical to mitigate arsenic pollution through technologies developed in arsenic-affected regions. Financial and social limits pose significant obstacles to the use of technology to mitigate arsenic pollution mitigation. Many arsenic removal techniques, such as membrane filtration, coagulation, and adsorption, are technically needed for complex infrastructure and maintenance, which may not be possible in environments with limited resources. The financial burden of implementing and maintaining these technologies can be unaffordable, especially in developing nations such as Bangladesh. Adopting new technology is sometimes hampered by local ideas and customs, which can also be important but frequently overlooked factors. These include lack of awareness, sociocultural factors, community acceptability, and involvement. However, there are enough chances for innovation and advancement. Technological developments that are affordable and easy to utilize present attractive options for reducing arsenic exposure. Novel adsorbents, solar oxidation, biosand filters, etc. are some examples of emerging techniques that have the potential to remove arsenic in a way that is more accessible and sustainable. To improve acceptability and long-term success, there is also a growing understanding of the importance of including community education and participation in technology adoption techniques. This chapter emphasizes the necessity for a multidisciplinary strategy that integrates technological innovation, economic viability, and sociocultural sensitivity while focusing on the possibilities and limitations of implementing arsenic technology.