It is axiomatic that advancements in agriculture can positively impact on food security, employment creation and the foreign exchange earnings of a country, among others. It was for these reasons that the government of Ghana introduced its flagship programme, ‘Planting for Food and Jobs’ (PFJ), in 2017, which was anchored on five key principles—supply of subsidised certified seeds, supply of subsidised fertilizer, e-agriculture, market opportunities, and free extension services. Existing studies have focused exclusively on the programme’s nature and its success in food security and jobs creation. Previous studies have not provided space for the politics of the programme. This chapter aims at situating the PFJ initiative within the context of political economy. Its overriding objective is to determine the extent to which political variables animate the nature and outcomes of the programme. The chapter employs exploratory study design to examine the politics of the PFJ, with data triangulated from multiple sources. The key findings are that the PFJ programme is highly partisan, and that it lacks a national character and legal framework to make it binding on successive governments. It concludes that the infusion of politics into the programme is a stumbling block to its success and longevity.