The combination of topology structural optimization and additive manufacturing (AM) technology has been unlocking unlimited potential for the fabrication of customized products, complex shapes, lightweight structures, and cost-effective solutions, especially in the fields of industrial production, high-tech, aviation, and space. This method has been of interest to technical designers because it can eliminate unnecessary bonding areas, significantly reducing product volume. This not only saves materials but also improves performance, ensuring the product meets necessary requirements such as rigidity, mechanical properties, and load capacity. In this study, the authors used ANSYS software to analyze, simulate, and optimize the topology to reduce the volume of the Crane Hook product. Five different degrees of binding gradually decreasing from 70%, 60%, 50%, 40%, and 30% are used to evaluate the load capacity of the product after optimization, fabricated by additive manufacturing 3D FDM and polylactic acid (PLA). Consequently, the product’s weight decreased from 74.67 to 34.13 g, representing a reduction of 48.65%. This reduction was achieved while still meeting the original requirement of sustaining a load of 500 N for 5 min, with a safety factor of 3.2148.