Crop Production is faced with yield decline arising from soil contamination, through heavy metal pollution from sundry human activities. This is allied with food insecurity and environmental risk. The advent of nanoparticles in agriculture has provided an all-encompassing sustainable management of heavy metal contaminants. Several commendatory reports abound on the positive effects of nanoparticles and nanosensors as heavy metal remediators; therefore, an overview of all these benefits on heavy metal remediation examined in this chapter, with relevance to plant health and soil quality improvement. The complexities and drawbacks of each remediation technique are equally evaluated.