HIV Disease and the Mouth
摘要
Human Immunodeficiency Virus (HIV) is a single-stranded RNA virus recognised for its transmissibility via blood or bodily fluids, including sexual transmission. HIV primarily infects certain white blood cells called CD4+ T lymphocytes, which are important in maintaining an effective immune system. Once entering the body, the virus recognises the CD4 molecule on these cells, binds to it and infects it with the virus. Once the virus is inside the cell, it replicates copies of itself, which are then released from the cell upon its death. The newly formed viruses go on to infect other CD4+ T lymphocytes. As T lymphocyte numbers decrease, the immune system loses its function, leading to acquired immunodeficiency syndrome (AIDS).