The sharp rise in electronic waste (e-waste) creates major environmental concerns, stemming from the accumulation of hazardous substances and the depletion of valuable materials. It encompasses discarded outdated electronic devices, and improper management of this waste leads to significant environmental pollution and poses potential risks to human health. Many electronic devices are designed with limited durability, making them outdated quickly. The increasing prevalence of bacterial infections, and toxicological and environmental impacts, alongside the anticipated growth of e-waste trends, highlights the urgent need to address this issue with effective policies and sustainable waste management practices. Bioleaching represents a transformative method for e-waste organization within a bio-circular economy context, highlighting sustainability and resource recovery. It can be adapted to various types of e-waste, assembling it as a multipurpose solution for labelling the growing waste crisis. This process exploits the metabolic activity of bacteria and fungi, which can solubilize metals like lead, nickel, aluminium, and lithium from complex matrices seen in electronic components. Bioleaching presents a promising alternative that is both eco-friendly and cost-effective for the recovery of precious minerals. It ensures that valuable materials are reclaimed and reused rather than discarded. This is a key solution to the challenges modelled by e-waste in our increasing society. This chapter offers a detailed summary of the various sources of e-waste and explores the bio-recovery of precious minerals through bioleaching, highlighting its economic significance.