One of the most serious and significant challenges of diabetes health care is diabetic foot ulcers (DFU). DFU is more difficult to cure, especially for those who already have a compromised immune system, and therefore often leads to chronic wounds if not effectively controlled. Meanwhile, laser therapy provides a non-invasive method to reduce infection in these wounds. This proposed study aims to simulate standardized diabetic ulcer models using computational software. The simulations will involve evaluating the wavelengths of laser with different pulse widths for their effectiveness in curing diabetic ulcers. Evaluation parameters such as wound closure rate, inflammation, angiogenesis, and collagen deposition were simulated and analyzed to determine the optimal laser wavelength, frequency, and pulse width for diabetic ulcer treatment. The findings of this simulation study could offer valuable insights for clinical practice, and have the potential to improve patient outcomes in the management of diabetic ulcers.