Distal radial access (DRA) in the anatomical snuffbox is gaining increasing acceptance as an alternative to conventional transradial access (TRA) for cerebral and coronary angiography and interventions. This chapter describes the learning curve for DRA, highlighting that complication rates during the learning curve are low, with no major adverse event reported. A comparison of left and right DRA is also presented, and the advantages of DRA over conventional TRA are outlined, emphasizing that with commitment and proper technique, a high success rate can be achieved, making it a safe and valuable alternative access in interventional cardiovascular medicine.