An investigational study on the viability of Eggshell Powder (ESP) as a partial replacement for Ordinary Portland Cement (OPC) in M40 grade concrete has been conducted to evaluate its impact on cost reduction and compressive strength retention. The choice of ESP sourced from poultry industries as a substitute material was motivated by its chemical similarity to limestone. This research involved casting M40 grade concrete cubes in accordance with IS 10262:2009 standards with cement being partially replaced by ESP in varying proportions of 0, 5, 10, 15, and 20%. Additionally, supplementary cementitious material (SCM) Metakaolin was incorporated up to a 20% replacement level with the resulting average compressive strengths recorded at 45.53, 50.18, 51.37, and 30.46 N/mm2. The compressive strength of these specimens was assessed after 28 days of moist curing and compared against that of traditional concrete. These outcomes were juxtaposed with the compressive strength of conventional concrete, elucidating the potential of ESP in concert with SCMs like Metakaolin to curtail cement consumption while preserving the structural integrity of concrete. This inquiry positions ESP amidst other cement-reducing agents such as Rice Husk Ash, Fly Ash, and Silica Fumes, underscoring its promising capacity to diminish cement dependency in concrete formulations without detriment to its fundamental properties.