This chapter illustrates various kind of printed antennas like microstrip, dipole, fractal, conformal etc. used in wireless communication for 5G, IoT, and smart applications like smart agriculture, smart cities, monitoring systems, automotive applications, smartphones etc. as being cheap, light weightiness and simplicity in manufacturing. Following sections presents various antennas designed by researchers for 5G, IoT and smart applications. This chapter also gives some requirements and challenges for 5G communication. Overall, the objectives of 5G networks revolve around delivering higher data rates, lower latency, greater capacity, and improved connectivity for a wide range of applications, from enhanced mobile experiences to mission critical IoT deployments. Final section of this chapter provides design consideration like antenna size, operating frequency, multiband operation, optimization, MIMO consideration, testing etc. for integration of printed antennas in IoT and smart applications and various challenges facing by researchers on integrating antennas with other components for conducting consistent wireless communication and best system performance.