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The assumption of equally sized stages is quite restrictive. For example, although it might be planned to perform the interim analyses after stages of equal size, the schedule of interim analyses can often at best ensure that the stage sizes are roughly the same.

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Procedures with Unequally Sized Stages

  • 章节

  • 发表日期：

    2025年

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  • Gernot Wassmer,
  • Werner Brannath

摘要

The assumption of equally sized stages is quite restrictive. For example, although it might be planned to perform the interim analyses after stages of equal size, the schedule of interim analyses can often at best ensure that the stage sizes are roughly the same.