Small and medium-sized enterprises (SMEs) play a significant role in global economic development and have considerable potential to contribute to sustainability goals. However, they often face unique challenges in implementing sustainable practices due to limited resources and competing priorities. This chapter presents a strategic approach to sustainability implementation in SMEs, combining the United Nations Sustainable Development Goals (SDGs) as a strategic framework with the UN Sustainable Development Performance Indicators (SDPI) as a context-based impact measurement system. We argue that successful sustainability implementation requires more than isolated initiatives—it demands clear strategic direction and meaningful performance measurement. The chapter demonstrates how organizations can use the SDGs to develop focused sustainability strategies while determining appropriate ambition levels that align with their capabilities and objectives. Using https://www.malik-management.com/malik-solutions/malik-tools-and-methods/malik-direttissima/ ), we provide practical guidance for integrating sustainability considerations into strategic processes while maintaining adaptability in complex environments. Remark: In this chapter, we refrain from using the Three-Pillar Model (description in Chap. 2 ) practiced here in the other chapters and instead choose the aforementioned Malik model. A key contribution of this chapter is its detailed examination of the UN SDPI framework as a transformative tool for sustainability impact measurement. Unlike traditional approaches focused on incremental improvements, this framework enables organizations to understand whether their efforts truly contribute to sustainable development through context-based thresholds and transformative indicators. We provide practical guidance for implementing this framework effectively, including data collection and analysis approaches that consider SMEs’ resource constraints. The chapter addresses both opportunities and challenges of implementation within the current regulatory landscape, including requirements such as the Corporate Sustainability Reporting Directive (CSRD), EU Taxonomy, and Sustainable Finance Disclosure Regulation (SFDR). By adopting this strategic approach, SMEs can enhance their competitiveness and resilience while making meaningful contributions to sustainable development.