This article aims to analyze the adverse events and cause of failures involving pulse oximeters during their use and propose strategies for Clinical Engineering seeking to mitigate risks and make the environments in which the device is used safer. The pulse oximeter is a medical device widely used in various healthcare establishments, being extremely relevant for clinical decision-making. However, for its use to be safe, its operation must be adequate and the results reliable. An analysis of service orders and reports of failures in Health Centers in Florianópolis was carried out, as well as an evaluation of techno-surveillance notifications in ANVISA and MAUDE/FDA databases to understand the main problems highlighted. The Ishikawa Diagram quality tool was applied to assist in developing strategies to mitigate risks to patients. Actions such as best practice manuals and webinars were developed by IEB-UFSC, and as future work, this work aims to develop resources with augmented and virtual reality and integrate data into a ubiquitous platform with interoperability between health data.