The chapter synthesizes key findings and future directions regarding the intersection of Long COVID fatigue and brain health research. It emphasizes the critical importance of screening for Long COVID fatigue in brain health and dementia studies, particularly those involving brain stimulation and neuroimaging. The text outlines six principal research priorities: developing standardized screening tools, investigating underlying mechanisms, identifying risk factors, conducting longitudinal studies, developing targeted interventions, and fostering international collaboration. The chapter concludes by framing Long COVID fatigue not only as a challenge but as an opportunity to advance understanding of brain health and human resilience. It advocates for a coordinated global response that emphasizes data sharing, standardization, and interdisciplinary collaboration to address the long-term neurological consequences of the COVID-19 pandemic.